Research Associate Kouzarides Group

Closing date:

Research Associate

STORM Therapeutics is a University of Cambridge spin-out, translating the ground-breaking work of Professors Tony Kouzarides and Eric Miska in RNA epigenetics into the discovery of first-in-class drugs in oncology and other diseases. At the core of the company’s R&D strategy is a close collaboration with its scientific founders at the University of Cambridge to establish a leadership position in the field of RNA modifying enzymes and build a unique biology platform for the discovery of new drug targets. The company draws on these unique insights to develop small molecule inhibitors for the treatment of specific cancers with high unmet medical need.

We are now looking to recruit an enthusiastic post-doctoral scientist, embedded in the group of Professor Kouzarides. The Kouzarides group is working at the forefront of research into the molecular pathogenesis and genetic vulnerabilities of aggressive cancers, with a focus on RNA epigenetic mechanisms (Barbieri et al Nature 2017, Xhemalce et al Cell 2012). Our research is strongly translational. We are applying an integrated approach, using CRISPR genetic screens, biochemistry and cell biology, to understand how RNA-modifying enzymes drive carcinogenesis and to validate them as novel therapeutic targets for cancer.

Candidates must have experience in molecular and cancer biology, and a PhD in the biological, biochemical or biomedical sciences. Previous experience with RNA biology, genetic screen approaches and animal models would be beneficial.

Fixed-term: The funds for this post are available for 2 years.

Essential Skills

  • PhD in biological or biochemical sciences (or similar)
  • Experience in a research environment with a good publication track record
  • In depth knowledge of flow cytometry
  • Experience of CRISPR methods and screening
  • Experience with in vitro, ex vivo and in vivo work
  • Strong team player skills required
  • Highly organised and efficient with deadlines

Candidates should be legally entitled to work in the UK. Storm Therapeutics offers an industry competitive salary and benefits package.

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